| Ensembl ID | HGNC symbol | DBD Family | Is TF? | TF Assessment | Binding Mode | Motif Status | Notes | Comments |
|---|---|---|---|---|---|---|---|---|
| KMT2A | CxxC; AT hook | Yes | Known motif | 1 Monomer or homomultimer | High-throughput in vitro | Contains 3 AT-hook domain, a CXXC domain, and a possible C2H2 domain. | ||
| KMT2B | CxxC; AT hook | Yes | Likely to be sequence specific TF | 1 Monomer or homomultimer | No motif | Structural evidence shows direct DNA-binding (PDB:4PZI) and KMT2B appears to make specific contacts with methylated DNA. |